Post-Acute COVID Vaccination Syndrome (PACVS): Biomarkers Uncovered

Broadcast Message

Study finds elevated anti-spike antibodies in Post-Acute COVID Vaccination Syndrome (PACVS) patients, not from natural infection. Symptoms appear 10 days post-vaccination and last 20 months, including fatigue, neurological issues, and skin problems. Key autoantibodies linked to specific symptoms suggest immune mechanisms targeting human receptors. Authors advocate for testing and detox methods to address Spike protein effects, urging public health action.

Post-Acute COVID Vaccination Syndrome (PACVS): Biomarkers Uncovered New study links PACVS to the vaccine-induced Spike protein, uncovering autoimmune dysregulation and chronic, persistent symptoms. Tue, 17 Dec 2024 23:50:13 GMT https://petermcculloughmd.substack.com/p/post-acute-covid-vaccination-syndrome by Nicolas Hulscher, MPH

The study titled, Autoantibodies Targeting G-Protein-Coupled Receptors and RAS-Related Molecules in Post-Acute COVID Vaccination Syndrome: A Retrospective Case Series Study , was just published in the journal Biomedicines :

Here’s what they found:

Elevated Spike Antibodies vs. Nucleocapsid Antibodies Patients with PACVS show markedly elevated anti-spike (S) antibodies (mean= 3011.2 BAU/mL) and minimal anti-nucleocapsid (N) antibodies (mean = 0.4 BAU/mL) . This confirms symptoms arise post-vaccination , not from natural SARS-CoV-2 infection. The study found a positive correlation between anti-spike (S) antibodies and ACE2 autoantibodies , suggesting an anti-idiotype mechanism where the immune response to the Spike protein triggers autoantibodies targeting ACE2. Additionally, elevated Spike antibody levels were associated with specific symptoms, such as widespread burning sensations .

PACVS Symptoms Began days to weeks after vaccination (median onset: 10 days). Persisted for a median of 20 months (range: 4–32 months), demonstrating the chronic nature of this syndrome.

Symptoms included:

Chronic fatigue and mental fog

Memory loss and neurological symptoms

Tachycardia, hypertension, and cardiovascular issues

Widespread burning sensations and neuralgia

Skin symptoms: bruising, edema, and rashes

Key Autoantibodies and Associated Symptoms The authors emphasize that the Spike protein can trigger autoimmunity through mechanisms such as molecular mimicry , where the immune system mistakenly targets human receptors.

ACE2 Autoantibodies

Linked to:

Skin bruising

Skin edema and rashes

Hypertension

MAS1 Autoantibodies

Linked to:

Widespread burning sensations

ATR1 Autoantibodies

Linked to:

Lymphadenopathy (swollen lymph nodes)

STAB1 Autoantibodies

Linked to:

Skin edema and rashes

ADRA2A Autoantibodies

Inversely associated with:

Memory loss and mental fog

These data confirm that Anti-spike antibody testing and autoantibody panels (ACE2, MAS1, ATR1, STAB1, ADRA2A) offer measurable biomarkers to identify PACVS. They also solidify the rationale for detoxifying the body from the highly pathogenic and persistent Spike protein (demonstrated by over 250 peer-reviewed studies ) with Base Spike Detoxification :

Our public health agencies must finally begin to address the widespread Spike protein poisoning of the population. This includes developing affordable and accessible Spike protein tests and launching large-scale, prospective, double-blind, placebo-controlled trials to identify effective methods for clearing the Spike protein from the body.

Nicolas Hulscher, MPH

Epidemiologist and Foundation Administrator, McCullough Foundation

www.mcculloughfnd.org

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